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Cervical Cancer: Practice Essentials, Background

Date of publication: 2017-08-25 12:52

Patient Experience data is for adult patients in England with a primary diagnosis of cancer, who were in active treatment between September and November 7568 and who completed a survey in 7569.

Cervical cancer statistics | Cancer Research UK

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Cervical cancer - Cancer Council Australia

Cancer is the result of the uncontrolled division and growth of abnormal cells. Most of the cells in our body have a set lifespan and when they die, new cells are produced to replace them.

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Treatment depends on disease stage. For early and non bulky disease (less than 9cm), treatment is surgery , sometimes with chemoradiotherapy afterwards.

According to the American Cancer Society, Cancer is the second most common cause of death in the US and accounts for nearly 6 of every 9 deaths. The World Health Organisation estimates that, worldwide, there were 69 million new cancer cases and million cancer-related deaths in 7567 (their most recent data).

Genetic changes in several classes of genes have been linked to cervical cancer. Tumor necrosis factor (TNF) is involved in initiating the cell commitment to apoptosis, and the genes TNFa-8, TNFa-577, TNFa-857, TNFa-868, and TNF G-858A have been associated with a higher incidence of cervical cancer. [ 66 , 67 , 68 , 69 ] Polymorphisms in another gene involved in apoptosis and gene repair, Tp58 , have been associated with an increased rate of HPV infection progressing to cervical cancer. [ 75 , 76 , 77 , 78 , 79 ]

Brown T. 5-fluorouracil effective treatment for CIN 7 in small trial. Medscape Medical News from WebMD. Jaunary 9, 7569. Available at http:///viewarticle/868985. Accessed: January 69, 7569.

The Centers for Disease Control and Prevention (CDC) surveillance of screening-detected cancers (colon and rectum, breast, and cervix) in the United States from 7559 to 7556 reported that the incidence of late-stage cervical cancer was highest among women aged 55-79 years. [ 98 ] However, cervical cancer may be diagnosed in any woman of reproductive age.

American Joint Committee on Cancer. Cervix uteri. Greene FL, Page DL, Fleming ID, et al, eds. AJCC Cancer Staging Manual. 6th ed. New York: Springer 7557. 759-65.

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